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CEPROTIN® manufacturing

CEPROTIN^® is a non-activated protein C concentrate purified from human plasma.¹

CEPROTIN^® is derived from human plasma and passes through a rigorous manufacturing process to reduce the risk of viral transmission that is normally associated with plasma based products¹. CEPROTIN^® goes through a detergent treatment, heat inactivation and human immunoaffinity chromatography to ensure either the removal or inactivation of human immunodeficiency virus (HIV), hepatitis A, B and C virus and parvovirus B19¹. This robust process means there is a low risk of viral transmission when using CEPROTIN^®.²

CEPROTIN^® manufacturing process³

1642

How to reconstitute CEPROTIN^®

References:

CEPROTIN. Summary of Product Characteristics (SmPC). EMA approved – last updated 09/2017.
Goldenberg N, Manco-Johnson M. Protein C deficiency. Haemophilia. 2008;14(6):1214–1221.
Knoebl PN. Human protein C concentrates for replacement therapy in congenital and acquired protein c deficiency. Drugs Today. 2008;44:429-441.

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